Chk1 antibody
WebCHK1 (CHEK1) is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. CHK1 can also phosphorylate p53 at Ser20 in vitro. Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by proteolysis of cyclins. WebCHK1 (CHEK1) is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. CHK1 can also phosphorylate p53 at Ser20 in vitro. Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by proteolysis of cyclins.
Chk1 antibody
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WebCHK1 is phosphorylated on Serine 345 (S345) in response to UV, IR and hydroxyurea (HU). CHK1 plays an essential role in the mammalian DNA damage checkpoint, embryonic … WebHuman Phospho-Chk1 (S345) Antibody Summary Species Reactivity Human Specificity Detects human, mouse, and rat Chk1 when phosphorylated at S345. This antibody does not recognize Chk1 when unphosphorylated at S345. Source Polyclonal Rabbit IgG Purification Antigen Affinity-purified Immunogen Phosphopeptide containing human …
WebChk1 Antibody (D-7) is a mouse monoclonal IgG 1 κ, cited in 10 publications, provided at 200 µg/ml raised against amino acids 1-476 representing full length Chk1 of human … WebChk1 is involved in cell cycle arrest when DNA damage has occurred, and it plays an important role in DNA damage checkpoint, embryonic development and tumor suppression (1). Chk1 is activated in response to replication blocks and genotoxic stress, via phosphorylation of serines 317 and 345 (2).
WebSee all Chk1 primary antibodies Description Rabbit polyclonal to Chk1 (phospho S317) Host species Rabbit Tested applications Suitable for: IHC-P, WB, ICC/IF more details Species reactivity Reacts with: Human Immunogen Synthetic peptide. This information is proprietary to Abcam and/or its suppliers. Positive control WebChk1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when …
WebRabbit polyclonal Chk1 antibody. Validated in WB, IHC and tested in Human. Cited in 24 publication(s). Independently reviewed in 3 …
WebChk1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by Chk1 becomes bound by an adaptor protein in … foal nomination 2022WebMonoclonal Antibody for studying Chk1. Cited in 431 publications. Validated for Western Blotting, Simple Western™. Highly specific and rigorously validated in-house, Chk1 … foal name ideasWebChk1 kinase acts downstream of ATM/ATR kinase and plays an important role in DNA damage checkpoint control, embryonic development, and tumor suppression (1). Activation of Chk1 involves phosphorylation at Ser317 and Ser345 by ATM/ATR, followed by autophosphorylation of Ser296. greenwich commons riWebMouse anti Chk1 antibody, clone 2G1D5 recognizes Chk1 also known as cell cycle checkpoint kinase homologue 1, CHK1 or checkpoint kinase-1. Chk1, like the other checkpoint kinase Chk2, is a serine/threonine protein kinase that plays a crucial role in cell cycle control. Chk1 becomes phosphorylated and consequently activated in response to … foal nursing bayWebHuman Phospho-Chk1 (S345) Antibody Summary. Detects human, mouse, and rat Chk1 when phosphorylated at S345. This antibody does not recognize Chk1 when … foal nominationsWebWestern Blot: Chk1 Antibody [NB100-311] - Samples: Whole cell lysate (50µg) from 293T and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified goat anti-Chk1 antibody used for WB at 0.1µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. F721698.jpg. foal nursing cpdWeb20 hours ago · In addition, an anti–IL-8 antibody improved inflammation and fibrosis in a monkey model of endometriosis , ... H. Zhao, Dominant mutations in CHK1 cause pronuclear fusion failure and zygote arrest that can be rescued by CHK1 inhibitor. Cell Res.31, 814–817 (2024). Crossref. foal names\\u0027 horse