WebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia * hypomagnesemia *hypocalcemia *hypophosphatemia *fanconi-like syndrome * acute kidney injury We have all seen these complications on the renal consult service at least once. WebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated with …
Cisplatin induced hyponatremia; looking deeper - Renal Fellow …
WebApr 15, 2024 · Neurologically, very severe hypophosphatemia (<0.6 mg/dL) can contribute to paresthesia, altered mental status, encephalopathy, seizures and coma [ 14 ]. Depletion of ATP in the heart can result in depression of myocardial performance and tachyarrhythmias in patients with serum phosphate ˂1.5 mg/dL [ 15 ]. WebMay 19, 2024 · Frequently, hypocalcemia is associated with hypomagnesemia . Cisplatin can decrease 1-alfa-hydroxylation activity and result in low vitamin D3 levels. In cisplatin … ciberbullying unicef
DRUG NAME: Cisplatin - BC Cancer
WebApr 10, 2024 · Med-Surg Nursing. Hypocalcemia is when there are low levels of calcium in the blood. Calcium is an electrolyte that plays a vital role in many bodily functions, including muscle contraction, nerve transmission, and bone formation. Various factors, including nutritional deficiencies, medications, and underlying medical conditions, can all lead ... WebFeb 17, 2024 · A number of drugs sometimes cause hypocalcemia as a side effect. Some of these include the following: Certain drugs for osteoporosis ( bisphosphonates like zoledronate) 5 Some antiepileptic drugs Certain chemotherapy drugs (like cisplatin) Diuretic drugs (like furosemide) 6 Proton pump inhibitors WebJul 18, 2024 · Cisplatin causes hypomagnesemia in a dose‐dependent fashion and affects up to 90% of patients if no preventive measures are taken (see Section 5 below). 79 The etiology of cisplatin‐induced hypomagnesemia is not completely understood; renal Mg loss is the primary mechanism, but gastrointestinal losses have also been reported. 80 ... dgi chat en linea