Phospho sting

Web产品说明. The Human Monocyte STING Activation Flow Cytometry Panel includes antibodies targeting phospho-STING (Ser366) and phenotyping markers to enable observation of STING activation in human monocyte populations among peripheral blood mononuclear cells (PBMCs). CD45 is a pan leukocyte marker. Monocytes and dendritic cells (DCs) are ... WebHuman Monocyte STING Activation Flow Cytometry Panel 1 Kit #69210 (50 assays) Description: The Human Monocyte STING Activation Flow Cytometry Panel includes antibodies targeting phospho-STING (Ser366) and phenotyping markers to enable observation of STING activation in human monocyte populations among peripheral blood …

Phospho-STING (Ser366) cellular HTRF kit Cisbio

WebPhospho-STING (Ser366) one-plate assay protocol Detection of Phosphorylated STING (Ser366) with HTRF reagents can be performed in a single plate used for culturing, … WebPolyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Antibodies are purified by protein A and peptide affinity chromatography. Validations. None provided. Applications. Immunoprecipitation (IP) Western Blotting (WB) Reactivity. Homo sapiens … how many brands does anheuser busch own https://patriaselectric.com

Phospho-STING (Ser366) Polyclonal Antibody - Thermo …

WebThe Phospho-STING (Ser366) (D8K6H) Rabbit mAb Antibody was generated using stimulator of interferon response cGAMP interactor 1, and STING1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, Immunocytochemistry, and Immunofluorescence. WebPhospho-STING (Ser366) (D8K6H) Rabbit mAb (Alexa Fluor ® 647 Conjugate) recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species … WebSep 19, 2013 · This paper provides previously undescribed evidence that STING, an endoplasmic reticulum (ER)-resident protein involved in DNA sensing, couples ER stress … how many brandenburg concertos are there

Phospho-STING (Ser366) (D7C3S) Rabbit mAb 19781S from Cell …

Category:Western Blot Detection of Phosphorylation Events - Bio-Rad

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Phospho sting

Phosphorylation of innate immune adaptor proteins MAVS, STING, and …

WebPhospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide …

Phospho sting

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WebJun 7, 2024 · The assay showed the dependency of STING phosphorylation on the STING agonist, TBK1, “ER-to-Golgi” traffic, and palmitoylation, which mirrored the nature of … WebMar 25, 2024 · Stimulator of interferon genes (STING) contributes to immune responses against tumors and may control viral infection including SARS-CoV-2 infection.

WebThe interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages. In Cell Death & Disease on 28 July 2024 by Wu, J., Liu, Q., et al.. WebJun 7, 2024 · STING is also phosphorylated at Ser365 by ULK1, and this phosphorylation is required for the termination of the STING signalling 14. STING is an endoplasmic reticulum (ER)-localized...

WebThe Mouse Phospho-STING (Ser365) assay measures mouse STING when phosphorylated at Ser365. Unlike Western Blot, the assay is entirely plate-based and does not require gels, electrophoresis, or transfer. The Mouse Phospho-STING (Ser365) assay uses 2 labeled antibodies: one with a donor fluorophore, the other one with an acceptor. WebPhospho-STING/TMEM173-S366 Rabbit pAb (AP1223) Datasheet SDS. Tested applications: WB Reactivity: Human. Western blot analysis of THP-1, using Phospho-STING/TMEM173 …

WebSTING (TMEM173), also called stimulator of interferon genes, is a transmembrane adaptor protein that plays an important role in the innate immune response against viral and bacterial infections. It has been shown that cyclic GMP-AMP synthase (cGAS) plays a key role in STING activation.

WebApr 8, 2024 · STING is composed of a short cytosolic N-terminal segment, a four-span transmembrane domain, a connector region and a cytosolic ligand-binding domain (LBD) … how many brands does costco ownWebPhospho-STING (Ser365) Antibody (PA5-117271) in WB Western blot analysis of extracts of THP-1 cells using Phospho-STING (Ser365) Polyclonal Antibody (Product # PA5-117271). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Product Details high protein diet weight lossWebJul 7, 2024 · The Stimulator of Interferon Genes (STING) pathway initiates potent immune responses upon recognition of DNA. To initiate signaling, serine 365 (S365) in the C … high protein diet unhealthyWebInterestingly, we found that STING interacts with both TBK1 and IRF3, and that mutations in STING that selectively disrupt its binding to IRF3 abrogate IRF3 phosphorylation without impairing TBK1 activation. ... IRF3 also bound to phospho-TBK1 [TRAF family member-associated NFκB activator (TANK)-binding kinase] (Fig. 4 E and G), which is a ... how many brands does jd ownWebInhibition of IDH3α enhanced the efficacy of chemoimmunotherapy by activating cGAS-STING pathway through regulating acidic tumor microenvironments. Preprint on Research Square on 11 October 2024 by Zhang, L., Dai, X., et al.. high protein diet to lose belly fatWebJan 29, 2015 · STING is an essential adaptor protein in the cytosolic DNA sensing pathway that also activates IRF3 . Recently, STING Ser 366 was shown to be important in IRF3 … how many brands does kraft heinz haveWebThe Mouse Phospho-STING (Ser365) assay measures mouse STING when phosphorylated at Ser365. Unlike Western Blot, the assay is entirely plate-based and does not require gels, … high protein diet while pregnant