WebPolypyrimidine tract-binding protein, also known as PTB or hnRNP I, is an RNA-binding protein. PTB functions mainly as a splicing regulator, although it is also involved in alternative 3' end processing, mRNA stability and RNA localization.[1] Two 2024 studies have shown that depleting PTB mRNA in astrocytes can convert these astrocytes to functional … WebSolution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA. Summary for 2ADB. Entry DOI: 10.2210/pdb2adb/pdb: Related: 2AD9 2ADC: Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 (2 entities in total) Functional Keywords:
High Glucose Suppresses Human Islet Insulin Biosynthesis by
WebApr 13, 2024 · AC006064.4–201 directly interacts with Polypyrimidine tract-binding protein 1 (PTBP1) in HCs. A Five proteins with highest pep score of AC006064.4–201 RPD-MS and their effects on Mmp13, Aggrecan, p21 and p53 assessed by western blotting analysis. B Coomassie brilliant blue staining of proteins binding to AC006064.4–201. WebTischendorf, J. J. W., Beger, C., Korf, M., Manns, M. P., & Kr ger, M. (2003). Polypyrimidine tract-binding protein (PTB) inhibits Hepatitis C virus internal ribosome ... cyfluthrin vs deltamethrin
Polypyrimidine-tract-binding protein: A multifunctional RNA-binding …
WebHere, we perform a targeted CRISPR screen of RNA-splice factors implicated in EC activation, and identify polypyrimidine tract binding protein (Ptbp1, or hnRNP I) as a critical mediator of EC activation, responsible for … WebWe show that H19 serves as a lipid sensor by synergizing with the RNA-binding polypyrimidine tract-binding protein 1 (PTBP1) to modulate hepatic metabolic … WebWe show that intron definition and intronic polypyrimidine domains are important. • PTB bound to these polypyrimidine sites reduced export but splicing was unaffected. • The PTB-driven export inhibition was antiparallel to an export stimulatory pathway. • We propose that PTB can regulate pre-mRNA export by bridging distant PTB molecules. cyfn36 filter